The development of particles under spatially uniform electric field in a liquid is called electrophoresis. It is caused by a charged interface show between the molecule surface and the encompassing liquid. The rate of movement of molecule relies on upon the quality of the field, on the net charge size and state of the particles and furthermore on the ionic quality, consistency and temperature of medium in which the atoms are moving. As an analytical tool, electrophoresis is straightforward, fast and exceedingly sensitive. It is utilized scientifically to concentrate the properties of a solitary charged species and as a separation technique. It gives the premise to various analytical techniques utilized for isolating atoms by size, charge, or restricting fondness. Example for the partition of deoxyribonucleic corrosive (DNA), ribonucleic corrosive (RNA), or protein particles utilizing an electric field connected to a gel framework. Gel framework utilized primarily is polyacrylamide and agarose. DNA Gel electrophoresis is generally performed for investigative purposes, regularly after intensification of DNA by means of PCR, yet might be utilized as a preparative technique before utilization of different techniques, for example: mass spectrometry, RFLP, PCR, cloning, DNA sequencing or Southern blotching for further characterization.