Radio analytical Chemistry centres on the examination of test for their radionuclide content. Different strategies are utilized to cleanse and recognize the radioelement of enthusiasm through compound strategies and test estimation methods. The field of radio analytical Chemistry was initially created by Marie Curie with contribution by Ernest Rutherford and Frederick Soddy. They created Chemical Separation and radiation measurement methods on earthbound radioactive substances. Amid the twenty years that took after 1897 the ideas of radionuclides was conceived. Since Curie's opportunity, utilizations of radio analytical Chemistry have multiplied. Current advances in atomic and radiochemistry explore have enabled specialists to apply chemistry and nuclear systems to clarify nuclear properties and responses, utilized radioactive substances as tracers, and measure radionuclides in a wide range of kinds of tests. The significance of radio analytical science traverses numerous fields including chemistry, material science, pharmaceutical, pharmacology, biology, ecology, hydrology, geology, forensic analysis, barometrical sciences, archaeology, and engineering. Applications include: shaping and describing new components, deciding the period of materials, and making radioactive reagents for particular tracer use in tissues and organs. The continuous objective of radio analytical specialists is to grow more radionuclides and lower focuses in individuals and the earth.